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In Week 10 of the NFL, the fantasy football landscape saw several significant performances, injuries, and lineup changes. Chuba Hubbard had a standout game, while some young wide receivers struggled to make an impact. Here's a detailed look at the key takeaways from this week's action.

Chuba Hubbard had a career-highlight performance for the Carolina Panthers, rushing for 153 yards on 28 carries and scoring a touchdown. Hubbard's impressive form this season led to a four-year contract extension, making him a valuable asset for fantasy football managers. However, his backfield partner, Miles Sanders, suffered an ankle injury early in the second quarter and did not return. With the Panthers heading into their bye week, Jonathon Brooks is expected to play a more prominent role in future games due to Sanders' uncertain status.

In the Carolina Panthers' receiving corps, rookie wide receivers and tight ends had quiet outings. None of the young targets from the New York Giants or Carolina Panthers surpassed 50 receiving yards, pointing to a challenging day for fantasy managers relying on these players. The Panthers traded Jonathan Mingo to the Dallas Cowboys, simplifying their receiver rotation. If veteran Adam Thielen, who is on injured reserve, returns soon, he could further shake up the lineup when he takes over in the slot or outside receiver positions.

Other notable performances in Week 10 included Keenan Allen with 44 receiving yards over five receptions and Travis Kelce tallying eight receptions for 64 yards and a touchdown. Meanwhile, Aaron Jones contributed 88 rushing yards and two catches for 13 yards, while Courtland Sutton made six receptions for 70 yards and a touchdown. These consistent outputs kept fantasy managers relatively happy despite some team struggles.

Key injuries also marred Week 10. Panthers' tight end Ian Thomas exited at the end of the first quarter and did not return, leaving the team to rely on Ja'Tavion Sanders, who filled in adequately but remains a risky waiver wire pickup. The New York Giants had receiver Malik Nabers dealing with a hamstring issue and Darius Slayton sidelined due to a concussion. Both players hope to recover during the Giants' bye week, with a favorable schedule ahead for wide receiver fantasy points.

In Denver, rookie running back Audric Estime impressed, taking over primary early-down duties from Javonte Williams and Jaleel McLaughlin. Estime's performance, coupled with Williams' role relegation to third downs, suggests a shift in the Broncos backfield that fantasy managers should monitor closely.

The Buffalo Bills also had to dig deep into their wide receiver lineup due to injuries. Curtis Samuel and Mack Hollins saw increased roles, and tight end Dalton Kincaid faced a knee injury, potentially elevating Dawson Knox's value if Kincaid misses additional time.

Overall, Week 10 delivered a mix of breakout performances, disruptions from injuries, and strategic shifts that will keep fantasy football managers vigilant as they prepare for upcoming matchups.