Buffalo Bills tight end Dawson Knox is set to undergo surgery on his injured wrist, according to coach Sean McDermott. The timetable for Knox's return is uncertain as it is still too early to determine the extent of his absence.

Knox initially injured his right wrist in the Bills' Week 5 loss to the Jacksonville Jaguars. Despite the injury, he played in subsequent games, albeit with limitations in practice. In Sunday's game against the New England Patriots, Knox saw action on 63.4% of offensive snaps.

Knox, who is in his fifth season with the Bills, has caught 15 passes for 102 yards and one touchdown this season. However, his role as a receiver has diminished with the addition of first-round pick Dalton Kincaid. The Bills have increased their usage of 12 personnel, with the aim of having both Knox and Kincaid on the field simultaneously.

Unfortunately for the Bills, Knox's inability to hold onto a key fourth-down pass against the Patriots proved costly. Linebacker Ja'Whaun Bentley knocked the ball loose, contributing to the Bills' 29-25 loss.

With third-string tight end Quintin Morris also sidelined due to an ankle injury, the Bills will rely heavily on Kincaid to step up. Kincaid had a breakout performance in the game against the Patriots, recording a career-best eight receptions on eight targets for 75 yards. McDermott expressed his satisfaction with Kincaid's performance, highlighting the importance of his growing connection with quarterback Josh Allen.

The Bills' next game is against the Tampa Bay Buccaneers on Thursday at 8:15 p.m. ET. The team will have a short turnaround as they prepare to face a formidable opponent without Knox and potentially Morris. The loss of Knox will undoubtedly impact the Bills' offensive strategy, but with the promising emergence of Kincaid, there is hope for continued success.

It remains to be seen how long Knox will be sidelined following his wrist surgery, leaving the Bills with a significant void to fill at the tight end position.