Researchers at the Ulsan National Institute of Science and Technology (UNIST) have unveiled a groundbreaking study that could revolutionize cancer treatment. Their team, led by Professors Sebyung Kang and Sung Ho Park from the Department of Biological Sciences, has introduced nanodrones specifically designed to target and eliminate cancer cells.

The nanodrones, known as NK cell-engaging nanodrones (NKeNDs), have the ability to engage natural killer (NK) cells, which are the body's frontline defense against cancer. What sets these nanodrones apart is their precision in targeting cancer cells, acting as guided missiles to seek out and bind to these cells.

The researchers utilized AaLS protein cage nanoparticles as the foundation for the nanodrones. These nanodrones were then engineered with cancer-targeting and NK cell-recruiting ligands, named HER2 @NKeND and EGFR@NKeND respectively, which led to a breakthrough milestone in cancer treatment.

In laboratory tests, the nanodrones demonstrated their exceptional ability to selectively bind to different types of cancer cells while activating NK cells to eliminate the invaders. The researchers also conducted trials on mice, where the administration of HER2 @NKeNDs alongside human immune cells resulted in a significant slowdown in tumor growth without any adverse effects.

Professor Kang Se-byung expressed his excitement regarding the research's potential. He emphasized the possibility of customizing treatments for various cancers by utilizing these NK cell delivery nanodrones. The focus is not only on targeting cancer cells but doing so with precision and minimizing collateral damage.

The groundbreaking study, published in Nano Today, was made possible with support from various institutions and centers dedicated to scientific progress. This breakthrough opens the door to a new era in cancer treatment, where nanodrones could potentially play a crucial role in fighting this relentless disease.

With the development of these nanodrones, researchers are hopeful that they have found a significant weapon in the battle against cancer. The ability to specifically target and eliminate cancer cells provides a new avenue for innovative and effective treatments. As further research and experimentation continue, the potential impact of nanodrones in cancer treatment cannot be understated.