Renowned physician and microbiologist, Professor Martin Blaser, known for his extensive research on our relationship with microbes, recently delivered the annual Darwin Lecture at The Institute of Cancer Research, London. In a conversation with the ICR's Mark Jones ahead of the lecture, Professor Blaser emphasized the crucial role microbes play in maintaining human health.

With a focus on Campylobacter species and Helicobacter pylori, Professor Blaser, currently holding the Henry Rutgers Chair of Human Microbiome at Rutgers University, delved into how our partnership with microbes impacts our overall well-being. He highlighted that human life is intricately tied to the human microbiome, which aids in digestion, vitamin provision, immune system training, brain interaction, and defense against invading organisms.

Professor Blaser expressed concerns regarding the negative impacts of modern living on our microbiome, citing the overuse of antibiotics and consumption of antibacterial agents in diets as detrimental factors. He also raised awareness about the link between changes in the microbiome and the rise of diseases such as asthma, allergies, obesity, diabetes, neurodevelopmental disorders, and certain cancers like colon cancer.

Researchers, including those at the ICR, have explored how gut bacteria composition can affect cancer patients' susceptibility to treatment side effects and tumor growth. As the diversity of our bacteria is crucial for disease prevention, Professor Blaser stressed the need to preserve and restore microbial species that have been lost due to societal and medical advances.

Looking ahead, Professor Blaser urged for immediate action to address the decline in bacterial diversity, likening the crisis to climate change. He emphasized the importance of reducing technological harm to the microbiome and developing strategies to restore key organisms essential for human health.

The seventh annual Darwin Lecture, hosted by Professor Sir Mel Greaves, marked Darwin Day and showcased Professor Blaser's insights on the significant role of our microbiome in safeguarding human health for the future.