The Los Angeles Chargers are facing a string of injuries as they prepare to take on the Kansas City Chiefs in a critical divisional matchup in Week 4. Following a tough loss and with key players on the sidelines, the Chargers are up against a formidable challenge. The team's star rookie RT Joe Alt is set to miss time due to an MCL sprain, adding to the injury concerns that include quarterback Justin Herbert's aggravated ankle sprain and OT Rashawn Slater's strained pec. With a one-game suspension also affecting S Derwin James, the Chargers could potentially be without five key players as they face the Chiefs.

Under the leadership of coach Jim Harbaugh, the Chargers have shown promise with a 2-1 start to their season, emphasizing a physical, run-focused style of play. However, injuries are now posing a significant obstacle to their success. The absence of talented players like Alt, Slater, and James, coupled with Herbert's limitations due to his ankle injury, could jeopardize their ability to keep pace with the high-powered Chiefs offense led by star quarterback Patrick Mahomes.

As the week progresses, all eyes will be on the injury reports to assess the availability of key players for both teams. The Chiefs, who have had a challenging start to the season, are now presented with an opportunity to capitalize on the Chargers' injury woes and secure a victory that could propel them to a 4-0 record. With standout performers like Chris Jones and George Karlaftis positioned to take advantage of a weakened Chargers lineup, the stage is set for an intriguing showdown between these AFC West rivals.