In an exciting Week 12 of NFL action, football analyst Pete Prisco shares his predictions for all the matchups. With over 500 picks for the season, Prisco is riding high as he aims for another successful week. Let's take a look at some of the notable games on Prisco's radar.

In a crucial divisional showdown, the Jacksonville Jaguars and Houston Texans will battle it out for first place in the AFC South. While the Texans have dominated their recent matchups, winning 10 of the last 11 encounters, the Jaguars appear determined to turn the tide. Led by rookie sensation Trevor Lawrence, the Jaguars are coming off a strong performance, and Prisco predicts they will continue their momentum and take control of the division with a 27-23 victory over the Texans.

Another key matchup in Week 12 features the New Orleans Saints and the Atlanta Falcons. With both teams sitting at .500, this game holds significant importance for their divisional standings. Despite facing some injury concerns, the Saints possess a solid defense that Prisco believes will give them the edge. Although the quarterback situation isn't ideal for the Falcons, Prisco predicts the Saints will secure a 24-20 win behind their defensive prowess.

The Tampa Bay Buccaneers face off against the Indianapolis Colts in what is expected to be an intriguing battle. The Buccaneers, playing their second consecutive road game, will rely on their talented roster to overcome the Colts. Prisco acknowledges the Colts' advantage of a bye week but ultimately predicts a 30-21 victory for the Buccaneers, citing their superior overall team strength.

Prisco believes the Cleveland Browns will prevail in their matchup against the Denver Broncos. With the Browns sitting at 7-3 and the Broncos riding a four-game winning streak, this game holds significant playoff implications for both teams. Despite Browns rookie quarterback Dorian Thompson-Robinson making his first road start, Prisco expects the dominant Cleveland defense to stifle the Broncos' offense, resulting in a low-scoring affair and a 20-12 victory for the Browns.

As for the highly anticipated showdown between the Buffalo Bills and Philadelphia Eagles, Prisco envisions a closely contested game. The Bills, fresh off an impressive win over the Jets, will face the Eagles, who are playing on a short week after their victory against the Chiefs. Prisco predicts a high-scoring affair, with the Eagles ultimately coming out on top in a close 31-30 finish.

These are just a few of the exciting matchups that Prisco has analyzed for Week 12. As football fans gear up for this action-packed week, Prisco's picks provide some intriguing insights and predictions to keep an eye on.