In a recent update, NFL analyst Pete Prisco has shared his Week 16 picks, aiming to continue his impressive winning streak. With the holiday spirit in the air, Prisco received an early Christmas gift last week, going 9-5-1 with his picks against the spread and 12-4 straight up. As his ATS record reaches 110-103-11 and his straight-up picks record stands at 136-88, Prisco is feeling confident heading into the Christmas weekend.

One of the highly anticipated matchups in Week 16 is between the Los Angeles Rams and the New Orleans Saints. Prisco expects a tight game, acknowledging the Rams as one of the surprise teams of the season. Despite the Saints' struggles on the road, Prisco believes their defense will keep them in the game. Ultimately, Prisco predicts the Rams will come out on top with a narrow victory, projecting a final score of Rams 23, Saints 21.

Another crucial game in terms of playoff implications is the clash between the Pittsburgh Steelers and the Cincinnati Bengals. Prisco notes that the loser of this matchup will have their playoff hopes significantly diminished. Although the Steelers have struggled on offense throughout the season, the analyst suggests their defense will be their saving grace. Prisco picks the Steelers to win the game, with a projected score of Steelers 26, Bengals 23.

The Buffalo Bills, fresh off two consecutive victories against top teams, are set to face the Los Angeles Chargers. Prisco expects the Bills' impressive offensive performance to continue, highlighting their recent success. He anticipates quarterback Josh Allen bouncing back from a modest performance last week and leading the Bills to another victory. Prisco predicts a final score of Bills 31, Chargers 17.

In another matchup, the Atlanta Falcons will take on the Indianapolis Colts. Despite the Colts' recent success, Prisco shares his belief that the Falcons will find a way to clinch the win behind quarterback Taylor Heinicke. Prisco projects a close game, ending with a final score of Falcons 23, Colts 20.

Meanwhile, the Tennessee Titans, led by either Will Levis or Ryan Tannehill at quarterback, are set to face the Seattle Seahawks. Prisco acknowledges that the Titans could be facing some uncertainty at the quarterback position due to Levis' ankle injury. However, he remains confident in the Titans' ability to secure the victory, especially given the Seahawks' short week. Prisco predicts a final score of Titans 28, Seahawks 24.

The Minnesota Vikings and the Detroit Lions are gearing up for a crucial divisional matchup. Prisco believes the Vikings' defense will bounce back after a disappointing performance last week and contain Lions' quarterback Jared Goff. Despite a tough fight from the Lions, Prisco sees the Vikings prevailing in a late-game victory, with a projected score of Vikings 23, Lions 20.

In a somewhat underwhelming matchup, the New York Jets are expected to face off against the Washington Commanders. Prisco notes that both teams have had their struggles this season but ultimately leans towards the Jets, highlighting their stronger defense as a determining factor. Regardless of who plays quarterback for the Jets, Prisco anticipates a close, low-scoring game, ending with a final score of Jets 19, Commanders 14.

The Green Bay Packers, despite their recent struggles, are favored to win against the Carolina Panthers. Prisco acknowledges the Packers' defensive concerns but ultimately predicts a Packers victory, projecting a final score of Packers 26, Panthers 13.

The Cleveland Browns and Houston Texans are both fighting for their playoff lives in a significant matchup. Prisco leans towards the Browns, citing their solid performance with Joe Flacco at quarterback. Even in the case of C.J. Stroud returning for the Texans, Prisco expects the Browns to secure the win, projecting a final score of Browns 24, Texans 17.

Perhaps one of the most intriguing matchups of Week 16 is between the Jacksonville Jaguars and the Tampa Bay Buccaneers. Despite Trevor Lawrence's presence in the concussion protocol, Prisco believes the Jaguars' defense will slow down Buccaneers' quarterback Baker Mayfield enough to secure the win. Prisco predicts a close game, with a final score of Jaguars 23, Buccaneers 20.

The article continues with Prisco's picks for other games, including the Arizona Cardinals vs. Chicago Bears, Dallas Cowboys vs. Miami Dolphins, New England Patriots vs. Denver Broncos, Las Vegas Raiders vs. Kansas City Chiefs, Philadelphia Eagles vs. New York Giants, and San Francisco 49ers vs. Baltimore Ravens.

As fans eagerly anticipate the outcomes of these matchups, they will undoubtedly keep a close eye on Prisco's predictions to see if his winning streak continues through Week 16.