The Jacksonville Jaguars (8-3) are gearing up to take on the struggling Cincinnati Bengals (5-6) in a highly anticipated Monday Night Football matchup. The game, which will be held at EverBank Stadium in Jacksonville, Florida, is set to kick off at 8:15 p.m. ET. The Jaguars enter the game as 10-point favorites, according to the latest Bengals vs. Jaguars odds.

The Bengals have been dealing with the absence of starting quarterback Joe Burrow, who is out for the remainder of the year, contributing to their recent struggles. They have lost three consecutive games, dropping them to fourth place in the AFC North standings. The Jaguars, on the other hand, have been in fine form, winning seven of their last eight games and holding a comfortable lead in the AFC South standings over Indianapolis and Houston.

In terms of the all-time series between the two teams, the Jaguars currently hold a 13-11 edge over the Bengals. However, the outcome of this game will be determined on the field.

SportsLine's Projection Model, which has simulated this matchup 10,000 times, is providing valuable insights and predictions. The model, which has been highly successful in predicting NFL outcomes, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. It boasts an impressive record of 175-126 on top-rated NFL picks since the 2017 season and has been on a hot streak, going 29-18 since Week 7 of last season.

The model's success extends beyond just predicting straight-up winners. It has consistently ranked in the top 10 on NFLPickWatch for straight-up NFL picks and has outperformed more than 94% of CBS Sports Football Pick'em players on multiple occasions.

Moving on to the Bengals vs. Jaguars game, the model has made its predictions based on the available data. It is leaning towards the Under, with a projected total score of 38 points. Additionally, the model identifies one side of the spread as offering value, although the specifics of the pick can only be found on SportsLine.

For the Jaguars, wide receiver Calvin Ridley will be a key player to watch. He has been in fantastic form, recording five-plus catches, 85 or more receiving yards, and a receiving touchdown in his last two games. Ridley previously had a standout performance against Cincinnati when he played for the Atlanta Falcons in 2018, accumulating 54 receiving yards and two touchdowns.

On the Bengals' side, running back Joe Mixon will be looking to make his mark by extending his streak of games with 60-plus yards from scrimmage. He has already achieved this feat in 10 games this season, tied for the most among running backs. Mixon also has a remarkable record against Jacksonville, scoring six touchdowns in four career games against the Jaguars.

Wide receiver Ja'Marr Chase will also be someone to watch for the Bengals. Chase has been a consistent playmaker, especially on the road, scoring touchdowns in his last three away games and accumulating over 100 receiving yards in two of his last three road games.

As the game approaches, football fans and bettors alike will eagerly await the final outcome. With SportsLine's model providing valuable insights and predictions, betting enthusiasts will be able to optimize their strategies. Whether the favored Jaguars or the underdog Bengals come out on top, Monday Night Football promises to deliver an exciting matchup for fans all around.