In Week 13 of fantasy football, several sleeper plays have emerged with the potential for high returns. With key matchups and favorable situations, these players present an opportunity for fantasy managers to gain an edge in their lineups. Let's take a closer look at some of the top sleeper plays with upside for Week 13.

First up is Pittsburgh Steelers quarterback Kenny Pickett, who finds himself in a dream matchup against the Arizona Cardinals. The Cardinals have allowed the second-highest touchdown percentage in the league this season, making Pickett primed for a strong performance. Coming off a game where he threw for 278 yards with a completion rate of 72.73%, Pickett has the potential to record the second multi-touchdown game of his career. He could be a valuable option for fantasy managers in need of a streaming quarterback.

Another player to consider is Devin Singletary, the running back for the Buffalo Bills. After a limited role in Week 12, Singletary has a chance for a bounceback week against the Carolina Panthers. With a plus matchup against the Panthers' defense, Singletary could have the opportunity to make an impact and redeem himself in fantasy lineups.

In the tight end position, Houston Texans' Brevin Jordan is trending upward. With an injury to Dalton Schultz, Jordan could step into a starting role against the Denver Broncos, who have the best matchup for fantasy tight ends. This presents a favorable situation for Jordan to shine and potentially provide fantasy managers with much-needed points.

However, fantasy football managers should also note that Week 13 poses challenges due to bye weeks for several teams. The Buffalo Bills, Baltimore Ravens, Chicago Bears, Las Vegas Raiders, Minnesota Vikings, and New York Giants are all on a bye week, leaving fantasy lineups with limited options. Managers may need to explore the waiver wire to fill their lineups and make strategic moves.

Overall, Week 13 offers fantasy managers the chance to secure wins with well-placed sleeper plays. Keeping a keen eye on matchups and taking calculated risks can lead to significant rewards on the fantasy football field. As the season progresses, these sleeper plays with high upside could make a significant difference for fantasy teams vying for playoff spots.

(Note: All statistics and matchups mentioned are as of the provided information in the context.)