In a heartfelt message shared on X, renowned actress Christina Applegate opened up about her aspirations as she continues to fight against multiple sclerosis (MS). Applegate, best known for her roles in "Dead to Me" and "Married... with Children," revealed her desire to work with Shirley MacLaine and have shots with Cher, emphasizing the significance of making the most of her remaining days.

The 52-year-old actress disclosed her diagnosis of MS in August 2021, a chronic autoimmune disease that affects the central nervous system. Despite the challenges she has faced, Applegate expressed gratitude for the support she has received from fellow individuals battling the condition.

Since her diagnosis, Applegate has been transparent with her fans about how MS has impacted her daily life and career. In an interview with the New York Times in November 2022, she revealed that she had gained 40 pounds and required a cane to walk due to the disease. Applegate expressed her determination not to accept these changes, stating she is "pissed" about her condition.

Further sharing the effects of MS on her health, Applegate disclosed that she now wears diapers due to her loss of control over her bowels. In April, on her podcast "MeSsy," she revealed consuming a salad contaminated with fecal matter, which contributed to her condition. Despite these difficulties, Applegate remains resilient and continues to advocate for raising awareness about MS.

Applegate's battle against MS has also resulted in 30 lesions on her brain and the loss of circulation in her legs during a relapse. In light of these ailments, the Emmy-award winning actress openly admitted to not enjoying living life anymore. She later clarified that expressing her "dark thoughts" was crucial for her healing process, although assured her fans that she is not contemplating suicide.

As Christina Applegate bravely faces her health challenges, she remains an inspiration to individuals around the world. Her openness and transparency regarding her battle with MS not only raise awareness about the disease but also encourage others to support and empathize with those fighting their own health battles.

While it is uncertain what the future may hold for Christina Applegate, her determination to make the most of her remaining days accentuates the importance of cherishing every moment and pursuing one's dreams, no matter the circumstances.