In a shocking twist, Kayti Edwards, Matthew Perry's ex and former assistant, revealed that the late "Friends" star had an intense fear of needles and vowed never to use intravenous drugs. However, a federal investigation into Perry's death uncovered a startling revelation: he had been injected with ketamine at least 21 times during the last week of his life.

In an interview with the Mirror, Edwards recalled Perry's unwavering stance against needles, sharing how he expressed his aversion to injecting anything into his body. She admitted to often witnessing Perry being under the influence of various drugs, which deeply concerned her. Edwards even warned him about the dangers of mixing substances, fearing it could be fatal. Perry, however, was adamant that the only way one could die was through needle usage, assuring he would never engage in such activities.

Authorities have undertaken legal action, arresting and charging five individuals, including two doctors and Perry's assistant, in connection with his death from ketamine. The investigation revealed that Perry's then-assistant, Kenneth "Kenny" Iwamasa, administered the final dose of ketamine, causing the actor to pass out and tragically drown in his hot tub. Iwamasa, 59, has pleaded guilty to one count of conspiracy to distribute ketamine causing death, which could result in a prison sentence of up to 15 years.

Further details emerged with the arrest of Drs. Salvador Plasencia and Mark Chavez, along with "Ketamine Queen" Jasveen Sangha and alleged street dealer Erik Fleming. A text message obtained by law enforcement from Dr. Plasencia, an urgent care physician in Calabasas, California, shed light on the motive behind their actions and their apparent disregard for Perry's life.

At the time of his death, Perry had 3.54 micrograms per milliliter of ketamine in his bloodstream, equivalent to the amount used in general anesthesia. While ketamine is generally considered safe when administered by trained health professionals in a medical setting for conditions such as depression or post-traumatic stress disorder, Perry's final official visit for ketamine infusions had occurred over a week before his passing.

The revelation of Perry's ketamine use has left fans and loved ones puzzled and concerned. It raises questions about what led him to turn to this substance, despite his expressed fear of needles, and the motivations of those involved in his untimely death. As the legal proceedings unfold, the hope is that justice will be served and further insights gained into this tragic episode that has left a void in the hearts of many.