World's Most Powerful MRI Scanner Unveils Detailed Images of Human Brains

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ICARO Media Group
News
02/04/2024 18h29

The world's most powerful MRI scanner located in Saclay, France, has recently produced its first images of human brains, marking a significant breakthrough in neurological research. Developed by researchers at France's Atomic Energy Commission (CEA), this cutting-edge machine is expected to provide unprecedented precision and illuminate the mysteries of the human mind.

Previously used to scan a pumpkin back in 2021, the powerful MRI scanner called Iseult has now been greenlit by health authorities to scan human brains. Over the past few months, approximately 20 healthy volunteers have bravely ventured into the MRI machine, situated in the Plateau de Saclay area, south of Paris.

Dr. Alexandre Vignaud, a physicist involved in the project, expressed excitement over the level of precision achieved with Iseult. The machine utilizes an impressive 11.7 teslas magnetic field, surpassing the standard MRI scanners commonly found in hospitals, whose power typically ranges up to three teslas. This enhanced capability enables Iseult to capture images with ten times more precision than traditional MRI scanners.

Comparing images from Iseult to those from a regular MRI on a computer screen, Dr. Vignaud highlighted the newfound ability to visualize tiny vessels that supply the cerebral cortex and previously unseen details in the cerebellum. The machine's exceptional precision has astounded French Research Minister Sylvie Retailleau, herself a physicist, who believes this groundbreaking accomplishment will greatly improve the detection and treatment of brain pathologies.

Occupied within a 5-meter long and tall cylinder, Iseult houses a 132-tonne magnet powered by a coil carrying a current of 1,500 amps. With a spacious 90cm opening, humans can easily slide into the machine. The design of Iseult is the culmination of two decades of collaborative research between French and German engineers.

While the United States and South Korea are also working on similarly powerful MRI machines, they have yet to begin scanning images of humans. The primary objective of such advanced scanners is to refine our understanding of the brain's anatomy and identify the specific regions activated during different cognitive tasks.

Scientists have previously utilized MRIs to show how distinct regions of the cerebral cortex respond when the brain recognizes faces, places, or words. By harnessing the 11.7 teslas power of Iseult, researchers hope to explore the intricate relationship between brain structure and cognitive functions, such as reading or performing mental calculations, noted Dr. Nicolas Boulant, the project's scientific director.

Aside from enhancing our knowledge of brain structure and cognitive processes, Iseult's extraordinary capabilities may also provide insights into the mechanisms underlying neurodegenerative diseases like Parkinson's and Alzheimer's, as well as psychological conditions such as depression or schizophrenia. CEA researcher Anne-Isabelle Etienvre emphasized the potential of Iseult in understanding how cells function in specific areas of the cerebral cortex, such as the hippocampus, which is implicated in Alzheimer's disease.

Moreover, the scanner's strong magnetic field could offer a clearer image of how certain drugs, like lithium, distribute throughout the brain. By identifying which areas of the brain are targeted by drugs, such as those used to treat bipolar disorder, researchers aim to better personalize treatments and predict patient responses.

While Iseult's remarkable power is not intended for clinical diagnostic purposes, the knowledge gained from its use is expected to be applied in hospitals in the future. Although regular patients will not have immediate access to Iseult's capabilities, a new batch of healthy participants will be recruited in the coming months for brain scanning. It may be several more years before the machine is used on patients with specific medical conditions.

The unveiling of Iseult's detailed images of human brains promises to revolutionize the field of neuroscience, providing groundbreaking insights into brain function and neurological disorders. This extraordinary advancement in MRI technology brings us closer to unlocking the mysteries of the human mind and potentially transforming the diagnosis and treatment of various brain-related ailments.

The views expressed in this article do not reflect the opinion of ICARO, or any of its affiliates.

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