Official court documents have shed light on the last words of beloved Friends star Matthew Perry before his untimely passing. The actor, aged 54, died in October last year from the "acute effects of ketamine," a powerful anesthetic he was using for infusion therapy to treat his depression and anxiety. According to court records obtained by NBC News, Perry's final message to his long-term assistant Kenneth Iwamasa related to the fatal dose of ketamine.

Perry had reportedly asked Iwamasa to administer ketamine three times on the day he died, with his final request being, "shoot me up with a big one." Tragically, a few hours later, Perry was found unresponsive in his hot tub. These court documents came to light as Iwamasa, along with four others, was arrested and charged with providing the actor with the ketamine that led to his demise.

During a press conference, US attorney E Martin Estrada disclosed the identities of the suspects involved in the case. They included Perry's personal assistant, two doctors, and a woman known as "the Ketamine Queen" from North Hollywood, identified as Jasveen Sangha. According to the indictment unveiled in Los Angeles federal court, Perry's assistant, Iwamasa, and an acquaintance named Erik Fleming collaborated with doctors Salvador Plasencia and Mark Chavez to acquire large quantities of ketamine for Perry leading up to the fatal overdose.

The court documents further revealed that Perry had originally requested his first dose of ketamine at 8:30 am on October 28. Four hours later, while watching a film at his Los Angeles home valued at $5.3 million, he received his second dose. Subsequently, Perry asked Iwamasa to administer a third dose and prepare the hot tub. Iwamasa left the house briefly to run errands, only to return and discover Perry's lifeless body.

According to the indictment, Dr. Plasencia had administered ketamine to Perry in the past and even taught Iwamasa how to administer the drug in September. The documents suggest that Plasencia saw Perry as a lucrative opportunity, referring to the actor as a "moron" in text messages exchanged with Chavez before his death.

As the supply of ketamine became problematic for Plasencia, Perry's intermediaries turned to Sangha, the self-proclaimed "Ketamine Queen," who allegedly provided Perry with the fatal ketamine doses. The indictment states that in the days leading up to Perry's death, Iwamasa administered at least 15 ketamine injections obtained from Sangha.

Matthew Perry's death, initially ruled as accidental by a medical examiner, was considered a closed case. However, seven months later, an investigation was opened by federal and local authorities to determine the source of the ketamine that caused his fatal overdose. The investigation involved the Los Angeles Police Department (LAPD), the US Drug Enforcement Agency (DEA), and the US Postal Inspection Service (USPIS).

In December, Perry's autopsy report revealed that the level of ketamine found in his blood was consistent with amounts used for general anesthesia during surgeries. This finding raised questions as Perry's last infusion therapy had taken place one and a half weeks prior to his death, and the half-life of ketamine is significantly shorter.

The revelations from these court documents have ignited discussions regarding the ethical practices surrounding Perry's medication and the responsibility of those involved in procuring and administering his ketamine treatments. As legal proceedings unfold, the tragic loss of the beloved actor serves as a reminder of the complexities surrounding mental health treatment and the importance of ensuring the safety and oversight of medical procedures and prescriptions.

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